Scientific Research on Blue Light

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Blue light-blocking glasses are essential in our modern world. Numerous studies have found that blue light glasses have tremendous protective qualities.

Summary of the scientific research on blue-blocking glasses:

  1. Significantly improves sleep quality and insomnia symptoms
  2. Optimizes circadian rhythm
  3. Improve melatonin levels
  4. Reduced anxiety, depression
  5. Bipolar mania
  6. Protects: AMD (acute macular degeneration) phototoxicity
  7. Protects: Retina damage, cataracts
  8. Protects: DNA damage
Title Of StudyPublication Journal
Blocking nocturnal blue light for insomnia: A randomized controlled trial (2018) “Our underlying theory is that the reduction in blue-light exposure is the likely mechanism whereby amber lenses, compared to clear lenses, improve sleep in individuals with insomnia symptoms.”Journal of Psychiatric Research
Blue Blocker Glasses as a Countermeasure for Alerting Effects of Evening Light-Emitting Diode Screen Exposure in Male Teenagers (2014)  “We conclude that the use of [blue light-blocking] glasses in male adolescents while sitting in front of an LED screen in the evening can attenuate melatonin suppression and alerting effects before sleep. BB glasses therefore have the potential to acutely impede the negative effects modern lighting imposes on circadian physiology in the evening.”Journal of Adolescent Health
Protective effect of blue-light shield eyewear for adults against light pollution from self-luminous devices used at night (2015)  “Our results show that, according to some sleep indices, sleep quality is significantly better in healthy adults after using the blue-light shield eyewear while using self-luminous portable devices at night.”The Journal of Biological and Medical Rhythm Research
Blue blocker glasses impede the capacity of bright light to suppress melatonin production (2006)  “Blue blockers represent an elegant means to prevent the light-induced melatonin suppression.” “Our data show that, irrespective of gender, orange lens glasses can effectively block the capacity, of a 1-hr light pulse of 1300 lx in the eye, to suppress melatonin production.”Journal of Pineal Research
Amber lenses to block blue light and improve sleep: a randomized trial (2009)  “The amber lens group experienced significant improvement in sleep quality relative to the control group.”The Journal of Biological and Medical Rhythm Research
 Treatment of attention deficit hyperactivity disorder insomnia with blue wavelength light-blocking glasses (2013)  “Subjects completing the study showed subjectively reduced anxiety and improved sleep quality on multiple measures.”ChronoPhysiology and Therapy
Bigger, Brighter, Bluer-Better? Current light-emitting devices – adverse sleep properties and preventative strategies (2015)  “Both the orange-tinted glasses and the “sleep-aware” app significantly reduced short-wavelength emissions.”Frontiers in public health
Wearing Blue-Blockers in the Morning Could Improve Sleep of Workers on a Permanent Night Schedule: A Pilot Study (2010)  “Blue-blockers seem to improve daytime sleep of permanent night-shift workers.”The Journal of Biological and Medical Rhythm Research
 Use of modified spectacles and light bulbs to block blue light at night may prevent postpartum depression (2009)  “All new mothers may benefit from using glasses and light bulbs that block blue light when getting up at night to care for their babies.”Medical Hypotheses
Dark therapy for bipolar disorder using amber lenses for blue light blockade (2007)  “Use of amber lenses to produce evening ‘‘virtual darkness’’ should produce a circadian phase advance.”Medical Hypotheses
 Blue-blocking glasses as additive treatment for mania: a randomized placebo-controlled trial (2016)  “Blue Blocker glasses are effective and feasible as add-on treatment for bipolar mania.”Journal of Psychiatry and Neuroscience
 Recent studies provide an updated clinical perspective on blue light-filtering IOLs (2010)  “Implantation of blue light-filtering IOLs which mimic the natural human lens should be considered as a safe and relatively inexpensive preventive measure to reduce the potential risk for retinal phototoxicity and its associated potential risk for AMD in pseudophakia eyes.”Graefes Arch Clin Exp Ophthalmol


In this study, the researchers found that not only blue light but also green light is detrimental to sleep quality. If you want to optimize your circadian rhythm and have full protection from sleep robbing blue and green light at night we recommend using our RED Blue Blocking Sleep Glasses

Title Of StudyPublication Journal
Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor  “Polychromatic action spectra were reasonably consistent in indicating that the spectral region between 400nm and 550nm provides the strongest. stimulation of circadian and neuroendocrine responses.”
The Journal of Neuroscience


These studies showed how artificial light and blue light negatively affects our eye and health in general.

Title Of StudyPublication Journal
Evening light exposure to computer screens disrupts human sleep, biological rhythms, and attention abilities (2017)  “Given the widespread use of electronic devices today, our findings suggest that screen light exposure at evening may have detrimental effects on human health and performance.”Chronobiology International
Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption (2017)  “Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian system, which is deleterious to health.”  “The IARC has classified shift work in group 2A of “probable carcinogens to humans” since “they involve a circadian disorganization.”Life Sciences
Effects of Light on Cognitive Brain Responses Depend on Circadian Phase and Sleep Homeostasis (2011) “Shorter wavelength light exposure increases ongoing nonvisual cognitive activity in subcortical and cortical brain areas.”Journal of biological rhythms
Entrainment of the Human Circadian System by Light (2005) “Entrainment is a fundamental property of circadian systems by which the period of the internal clock is synchronized to the period of the entraining stimuli. An important aspect of entrainment in humans is the maintenance of an appropriate phase relationship between the circadian system, the timing of sleep and wakefulness, and environmental time (a.k.a. the phase angle of entrainment) to maintain wakefulness throughout the day and consolidated sleep at night.”Journal of biological rhythms
The Impact of Light in Buildings on Human Health (2010) “Exposure to light can have both positive and negative impacts on human health.”Indoor and Built Environment
Artificial light at night: a neglected population health concern of the built environment (2014)  “Artificial light at night (ALAN) is mentioned as disturbing sleep.”Health Promotion Journal of Australia
Brain Responses to Violet, Blue, and Green Monochromatic Light Exposures in Humans: Prominent Role of Blue Light and the Brainstem (2007)  “We demonstrate that a few tens of seconds of light induce immediate and significant wavelength dependent changes in brain activity.”PLOS one
What’s in a color? The unique human health effects of blue light (2010) “Some people consider the progress in the field of light and health over the last couple of years as the most important light induced innovation since the invention of the light bulb” Environmental Health Perspectives


While getting exposed to blue light from the Sun is beneficial as we explained in our Ultimate guide to blue light (The Sun is a balanced full spectrum light)

ultimate blue light guide

Today our modern technology uses a blue-rich unbalanced artificial junk light. These light sources such as LEDs, screens, TVs, smartphones, etc… have been shown to cause permanent eye damage

Title Of StudyPublication Journal
Research progress about the effect and prevention of blue light on eyes (2018) “short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration” “harmful blue light-induced effects on human eyes should not be ignored, blue light can also produce different degree of damage to corneal, crystal lens and retina. Therefore, it is necessary to take appropriate protective measures when using blue light-related products”International journal of ophthalmology
Retinal damage induced by commercial light-emitting diodes (LEDs) (2015) “The blue component of LED is the major cause of retinal damage” “LED light caused a state of suffering of the retina with oxidative damage and retinal injury. We observed a loss of photoreceptors and the activation of caspase-independent apoptosis, necroptosis, and necrosis”Free Radical Biology and Medicine
Removal of the blue component of light significantly decreases retinal damage after high intensity exposure (2018) “Retinal photodamage caused by a conventional light source (cold) can become chronic if exposure is high and long enough. In contrast, the use of blue-blocking filters can significantly alleviate the functional loss of retinal photosensitive cells. Therefore, these filters might be an effective mechanism to protect us from ocular pathologies”PLOS one
Influence of Light Emitting Diode-Derived Blue Light Overexposure on Mouse Ocular Surface (2016) “Overexposure to blue light with short wavelengths can induce oxidative damage and apoptosis to the cornea, which may manifest as increased ocular surface inflammation and resultant dry eye.”PLOS one
Bystander effects elicited by single-cell photo-oxidative blue-light stimulation in retinal pigment epithelium cell networks (2017) “blue LED light has been shown to induce more damage than white or green light, and induce ROS production and lipid peroxidation in RPE cells, resulting in apoptotic cell death. Finally, intense blue light can cause mitochondrial and nuclear DNA damage.”Cell Death Discovery


Blue light receptors are located in our eyes and throughout our skin. This is why it is recommended to wear long-sleeved clothes at night when exposed to blue light.

Artificial Blue light has been also shown to damage the skin.

Title Of StudyPublication Journal
Subcutaneous white adipocytes express a light-sensitive signaling pathway mediated via a melanopsin/TRPC channel axis (2017)  “It is clear that centrally mediated circadian rhythms play an important role in human health.”Scientific Reports
Blue Light Induces Mitochondrial DNA Damage and Free Radical Production in Epithelial Cells (2005)  “Blue light damage is not an uncommon feature of the skin and eye.”The Journal of Biological Chemistry

Jakab Jacsó
Jakab Jacsó

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